Ion Chromatograph (IC) with múltiple detection: High Resolution Mass Spectrometry (HRMS), Conductivity (CD) and Ultraviolet Visible (UV/VIS)

250.000 €

225.000 €

CERCA GINYS-III 008

The acquired infrastructure is an Ion Chromatograph (IC) with multiple detection: High Resolution Mass Spectrometry (HRMS), Conductivity (CD), and Ultraviolet/Visible (UV/VIS). The equipment includes the following devices:  Automatic sampler  Gradient pumps  Solvent generation system  Chromatography module  Detection system • o High Resolution Mass Spectrometer (HRMS) • o Conductivity detector • o Ultraviolet/Visible detector  Chromatographic system control and data processing

The infrastructure will provide participating centers with cutting-edge tools to address the challenges of environmental monitoring and medical assessment, and will therefore have a significant impact on their respective research strategies. Consequently, the sharing of their own and acquired knowledge, particularly in the computational field, will foster scientific growth and promote future collaborations for the development of new joint projects.

In response to the requirements established in European environmental regulation directives, the infrastructure will contribute to improving: · the understanding of environmental pollution problems and the prioritization of mitigation measures. · the development of new tools for monitoring the state of the environment and human health. · the management and operation of water treatment plants and purification plants through a more detailed assessment of micropollutants potentially hazardous to human health. · water quality and consumer confidence in public drinking water suppliers, which could lead to the additional benefit of reducing bottled water consumption. On the other hand, from a biomedical perspective, the IC-HRMS-CD-UV/VIS will facilitate: · the identification of biomarkers for more precise diagnosis, prognosis, assessment of severity, and monitoring of treatment and progression of cardiometabolic diseases (obesity, MASLD, diabetes), mental health diseases (depression, addiction, anxiety), neurodegenerative diseases (Alzheimer's disease, Parkinson's disease), cancer, or aging. · the evaluation of the pharmacokinetics, efficacy, and toxicity of new drugs. · the development of precision medicine through more personalized diagnoses and treatments.

In response to the requirements established in European environmental regulation directives, the infrastructure will contribute to improving: · the understanding of environmental pollution problems and the prioritization of mitigation measures. · the development of new tools for monitoring the state of the environment and human health. · With the support of: · the management and operation of water treatment plants and purification plants through a more detailed assessment of micropollutants potentially hazardous to human health. · water quality and consumer confidence in public drinking water suppliers, which could lead to the additional benefit of reducing bottled water consumption.

The activity channeled through the IC-HRMS-CD-UV/VIS is not limited to the exclusive scientific development of the project's participating centers, but is aligned with the analytical concerns of both other research organizations and the business community. The reason the infrastructure has been endorsed by numerous entities is its resolution capacity for the analysis of low-molecular-weight polar emerging contaminants, which is currently extremely in demand and difficult to perform using traditional instrumentation. The availability of the installed technology will assist cooperation between the interested parties, promoting strong relationships for the development of future collaborative projects, thus strengthening the research-business partnership.