Bioinformatics

The unit provides data processing and analysis for genomic, epigenomic and transcriptomic data microarrays and high performance sequencing Microarrays Genome SNV panels QC, variant call Custom genotype grouping Epigenome DNA methylation (450K, EPIC) • QC, Standardization • Methylation call (beta / M values) • Cluster • Differential methylation (DM / DMR) • Gene + Association of regulatory elements Transcriptoma Gene expression matrices • QC, Normalization • Quantification • Cluster • Differential expression • Analysis of the enrichment of the genetic set microRNA matrices • QC, Standardization • Quantification • Cluster • Differential expression • Target prediction • MiRNA-gene expression correlation High performance sequencing Genome Whole genome sequencing (WGS) Exome sequencing QC, Alignment Call variant Epigenome ChIP-seq, ATAC-seq, DNAse-seq QC, Alignment Call tap Differential binding Functional Analysis Whole Genome Bisulfite Sequencing (WGBS), Reduced Representation Analysis Bisulfite Sequencing (RRBS) QC, Cartography Methylation call Call variant Differential analysis (DMR / methyloma segmentation) Functional annotation Transcriptoma RNAseq (poly +/-, total) QC, cartography • Quantification Alternative splicing Cluster Differential expression Analysis of the enrichment of the genetic set Other consulting services Experimental design Statistical advice Analysis of workflow recommendations and tools Formation Internships Seminars Workshops

GINYS-IJC-005

Open