High resolution mass spectrometry

The High Resolution Mass Spectrometry Unit (HRMS) offers access to state-of-the-art mass spectrometry instruments capable of characterizing the wide range of compounds that are usually of interest to the Institute. The apparatus includes most of the ionization options, introduction of chromatographic samples and techniques that are necessary to solve problems of mass spectrometry in chemistry. In addition to the characterization of pure samples, the unit also supports research projects that depend more on mass spectrometry experiments, such as mechanical studies, intermediate identification, characterization of impurities or biochemical applications. In addition, the Unit offers a comprehensive training to guarantee an optimal use of the installations and an adequate interpretation of the data.

Facility

Liquid chromatograph coupled time-of-flight mass spectrometer

Waters Alliance HPLC coupled to MicroTOF Focus (Bruker Daltonics) with electrospray (ESI) and atmospheric pressure chemical ionization (APCI) options.

Liquid chromatograph coupled time-of-flight mass spectrometer

Waters LCT Premier liquid chromatograph coupled time-of-flight mass spectrometer (HPLC/MS-TOF) with electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) options.

MALDI time-of-flight mass spectrometerBRUKER Autoflex matrix assisted laser desorption ionization (MALDI) time-of-flight mass spectrometer.

BRUKER Autoflex matrix assisted laser desorption ionization (MALDI) time-of-flight mass spectrometer.

Liquid chromatograph coupled quadrupole-time-of-flight mass spectrometer. (UPLC-QqTOF)

Waters liquid chromatograph (UPLC) coupled to MaXis Impact (Bruker Daltonics) hybrid analyzer: quadrupole-time-of-flight mass spectrometer (UPLC/MS-QqTOF) with electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) options.

TimsTOF flexTM mass spectrometer (MALDI-ESI-Ion Mobility-MS)

TimsTOF flexTM, a tandem mass spectrometer with QqTOF geometry, incorporates trapped ion mobility separation and a dual source ESI/MALDI in a single instrument. MALDI source possess the Bruker SmartBeam™ 3D laser with true pixel fidelity for rapid, label-free MALDI imaging at high-spatial resolution. These unique features make timsTOF flexTM the platform of choice for OMICS studies, as there is not compromise between sensitivity and resolving power at maximum speed

Institutional Contacts / Head of Facilities

GC

Gisela Colet
Institut Català d'Investigació Química (ICIQ)

Provisional Contacts

Dr. Noemí Cabello | Manager |  ncabello@iciq.es  | 977 920 200 (ext. 302) |  ORCID  |  PRC Page 

Technician

Carly Chedotal |  cchedotal@iciq.es  | 977 920 200 (ext. 302)

Technicien

Vanessa Martínez |  vmartinez@iciq.es  | 977 920 200 (ext. 302)

Manager

Dr. Noemí Cabello |  ncabello@iciq.es  | 977 920 200 (ext. 302) |  ORCID  |  PRC Page 

Dr. Gisela Colet | Facilities Coordinator |  gcolet@iciq.cat  | Phone: +34 977 920 238

CERCA Institutes

Tarragona, Spain

2004

Institut Català d'Investigació Química (ICIQ)

Owners

Centres CERCA List

Address

https://iciq.org/research-unit/high-resolution-mass-spectrometry-unit/

Equipments & Services Offered

Elute UHPLC-timsTOF flex™ mass spectrometer (Bruker Daltonics) ESI/MALDI dual source and Coldspray Ionization coupled to ion mobility (IM). Coldspray ionization-Ion Mobility-MS: Unique combination for the analysis of ionic compounds at low temperature (up to -100 ºC), including separation of isomeric ions. MALDI Imaging – Ion Mobility-MS: Isomers separation / Isobaric ions. Determination of ions on surfaces. Liquid chromatograph coupled time-of-flight mass spectrometer Waters Alliance HPLC coupled to MicroTOF Focus (Bruker Daltonics) with electrospray (ESI) and atmospheric pressure chemical ionization (APCI) options. Liquid chromatograph coupled time-of-flight mass spectrometer Waters LCT Premier liquid chromatograph coupled time-of-flight mass spectrometer (HPLC/MS-TOF) with electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) options. MALDI time-of-flight mass spectrometer BRUKER Autoflex matrix assisted laser desorption ionization (MALDI) time-of-flight mass spectrometer. Liquid chromatograph coupled quadrupole-time-of-flight mass spectrometer. (UPLC-QqTOF). Waters liquid chromatograph (UPLC) coupled to MaXis Impact (Bruker Daltonics) hybrid analyzer: quadrupole-time-of-flight mass spectrometer (UPLC/MS-QqTOF) with electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) options.

Autoflex™ mass spectrometer: MALDI-TOF-MS m/z up to 70,000 Peptides and Proteins, Polymers, Oligonucleotides Low molecular weight molecules MaXis Impact™mass spectrometer (Bruker Daltonics) with ESI and APCI ionization sources. Coupled to an Acquity™ UPLC (Waters). ESI-QqTOF-MS ESI: Polar molecules, high and low molecular weight compounds. Proteins Organometallics. Non-Covalent Interactions MS/MS analysis. APCI- QqTOF-MS Medium Polarity Compounds, m/z up to 1500 MicroTOF™ mass spectrometer (Bruker Daltonics) with ESI, APCI and Coldspray ionization sources. Coupled to an Ultimate3000™ HPLC (Thermo Scientific). TOF-MS Coldspray ionization: analysis of ionic compounds at low temperature (until -100 ºC). Labile species, organometallic compounds, reaction intermediates. ESI/MALDI dual source and Coldspray Ionization coupled to ion mobility (IM) Coldspray ionization-Ion Mobility-MS: Unique combination for the analysis of ionic compounds at low temperature (up to -100 ºC), including separation of isomers. MALDI Imaging – Ion Mobility-MS: Isomers separation / Isobaric ions. Localization of ions on tissues.

Categorització

RIS3CAT domains & other

RIS3CAT Domains
CERCA GINYS Categories

GINYS-ICIQ-003

Access procedure & Fares

Open

https://iciq.org/wp-content/uploads/2025/08/RSA-01-2025_ENG.pdf

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