Proteomics

The Josep Carreras Leukaemia Research (IJC) Institute Proteomics Core is located on the Can Ruti campus, providing an exceptional translational research niche. The IJC Proteomics Core provides state-of-the-art mass spectrometry-based proteomics services to characterize and quantify proteomes, proteins, and their post-translational modifications. We offer proteomics services to Institute scientists and to external public and private organizations, delivered by a highly committed team.

Institutional Contacts / Head of Facilities

Provisional Contacts

Main Contact(s) of Facility

Ramón Díaz | rdiazp@carrerasresearch.org  | 93 557 28 00 Ext. 4200

Francesc Solé | Facilities Coordinator |  fsole@carrerasresearch.org  | (+34) 935572806 |  ORCID 

Owners

Centres CERCA List

Equipments & Services Offered

The Proteomics Core is equipped with an Exploris 480 mass spectrometer (Thermo Scientific) and two chromatographs, Evosep One (Evosep) and Vanquish Neo (Thermo Scientific), offering a versatile pipeline depending on sample analysis requirements, and a robust computational infrastructure and software. Additionally, the core offers a process automation-standardization service by means of Robot Biomeik5 (Beckman) and FastPrep-24 5G bead beating grinder and lysis system (MP Biomedical).

Services - Differential Proteomics expression using label-free or label-based techniques (e.g., TMT) - Identification and localization of Post-Translational Modifications (e.g., phosphorylation, ubiquitinylation, acetylation, and methylation) - Protein-protein interaction (i.e., Pull-down, BioID, Crosslink) - Extracellular vesicles from liquid samples (plasma and saliva) and cells - Targeted protein-peptide identification and quantification - Top Down (intact protein) - Monodimensional SDS-PAGE - Protein and AND/RNA extraction by FastPrep-24 5G bead beater - Process automation-standardization by Robot Biomeik5 (Proteomics, Genomics, and basic research) - Data analysis (differential expression and system biology) and Scientific support

Categorització

RIS3CAT domains & other

RIS3CAT Domains
CERCA GINYS Categories

GINYS-IJC-006

Access procedure & Fares

Open. Contact: Mon-Fri 08.30-17.30