2017-03-006 - CLIFE-1 GEL - Topical analgesic gel for anorectal pain relief

The invention relates to a topical gel composition comprising a local anesthetic agent and a non-steroidal anti-inflammatory agent, for use in the treatment of pre- and postoperative pain in the benign anorectal surgery, particularly, by topical rectal administration and using a specific dosage regime. It also relates to a specific topical lipogel composition which is especially suitable for this use.

2017-03-014 - rhsCD6SEPS - COMBINED CD6 THERAPY FOR TREATMENT OF INFECTIOUS DISEASES AND RELATED INFLAMMATORY PROCESSES (rhsCD6SEPS)

The invention discloses the therapeutic effects of the soluble ectodomain of CD6 (sCD6) in a lethal model of polymicrobial infection which leads towards a lethal Model of Polymicrobial Sepsis. Antimicrob Agents Chemother 61 (1): e01391-16). The results show time- and dose-dependent effects of sCD6 infusion on mouse survival post CLP induction, concomitant to reduced systemic inflammatory response and bacterial load, and most importantly The administration of shrCD6 has therapeutic potential for the intervention of septic shock syndrome and other inflammatory diseases, for which antibiotics have failed due bacterial resistances.

2017-03-004 - CARDIOCALP - CALPAIN INHIBITORS IN THE PREVENTION AND/OR TREATMENT OF VENTRICULAR REMODELLING

Calpain inhibition in the prevention and treatment of ventricular remodeling and heart failure. Chronic oral administration of a calpain inhibitor attenuates myocardial hypertrophy and fibrosis associated to adverse left ventricular remodeling related to both ischemic and non-ischemic cardiovascular disease.

2017-03-011 - iPole - Inertial-based, increased performance, surveying pole

IPOLE technology uses Kalman’s filter algorithms to combine GNSS (Global Navigation Satellite Systems) such as GPS, Galileo, Glonass and Boidu with accelerometers to overcome the critical restrictions that actual surveying poles face such as magnetic interferences produced by railways or electric power stations. IPOLE’s solution enables a superior velocity (no need to stop&go) and an increased area coverage thanks to an inclinable surveying pole (indoor electric) unaffected by magnetic fields.

2017-03-009 - 2shRNA - Bifunctional therapeutic shRNAs for drug resistance eradication

Bifunctional therapeutic shRNAs for drug resistance eradication. 2shRNA aims to deliver a novel RNA-based therapeutic approach with great potential to simultaneously knockdown two signalling pathways in cancer cells. The existing proof-of-principle was designed to fight HER2 positive breast tumours. The approach has involved bioinformatics studies, cycles of chemical refinement and biological evaluation in cell cultures of breast cancer tumours.

2017-03-008 - QDDP - Quantum Dots-based Diagnostics Platform

Kit for the diagnosis of different illnesses, based on hydrolytic properties of a biomarker (enzyme). A system of two populations of silica-embedded Quantum Dots (QD) (one of them quantifies the biomarker, the other is used as reference internal standard) are attached to a peptide sequence that incorporates a fluorescent colorant. A biomarker associated to the presence of a disease cleaves the peptidic linker, changing the fluorescent emission of the QDs proportionally to its concentration. Initial tests were performed with trypsin in stool samples as a biomarker for Cystic Fibrosis (CF).

2017-03-002 - GREENFUEL - CO2 reduction to methanol

Technology towards the transformation of CO2 into methanol as fuel in a neutral emission process

2017-03-003 + 2016-01-001 -GAS-1 : New Treatment Against Neutralizing Antibodies in Gram Negative Infections

Platform of Polymeric Conjugates for Selective Intracorporeal Removal of Specific Harmful Antibodies RemAb Therapeutics is a biopharmaceutical company whose main activities and expertise are related, among others, to the identification, characterization and selective removal of specific antibodies (HART-Technology) for offering health solutions in the field of infectious diseases, allergology, autoimmunity, transplantation and transfusion medicine, and modulation of the human immune responses against viral vectors.

2022-11-015 + 2018-04-015 + 2017-03-017 - ISCHEMBURG - 3 - Minimally-invasive microsensors for ischemia detection

ISCHEMSURG IS A DISPOSABLE MEDICAL DEVICE THAT CONTAINS A MINITURIZED ELECTRONIC SENSORS (SIZE LESSTHAN 1mm) FOR A MINIMALLY INVASIVE MONITORING OF TISSUE ISCHEMIA