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Advanced Microscopy Unit

The confocal microscopy service of the Josep Carreras Institute (IJC) is a newly implemented service that went into operation on June 5, 2023. The Confocal Microscopy team provides advanced services in the field of fluorescence microscopy to IJC researchers and in the near future, to external users, both from the Can Ruti campus (Badalona) and from other centers or public institutions and private The Unit is highly engaged with users through training and support in the technologies available at IJC, supporting the user individually in taking images. The individual training program carried out by the service staff allows users to be autonomous in the use of the microscope. In addition, the service staff is available daily for troubleshooting, technical support and any assistance.

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Cell immortalization

The Cell Immortalization Unit of the Josep Carreras Leukemia Research Institute offers B-cell infection with Epstein-Barr virus (EBV) which leads to further and subsequent immortalization. This is considered the method of choice for generating lymphoblastoid cell lines (LCL). Cell culture is an essential tool for studying the fundamentals of genetic background variables. With the development of personalized medicine, this is increasingly applied to the development and safety testing of drugs. Immortalized cells are derived from primary cells, thus establishing an immortalized cell line to achieve cultured cells in vitro. The purpose of unlimited proliferation and no difference between cells. The Cell Immortalization Unit works closely with you in an integrated manner starting with the project discussion (including the project outline and experimental design). we are continuously working to optimize standard operating procedures and implement the latest methodologies. With our personalized service, you can get our high quality customer service experience with high success rates, frequent communication and fast deadlines.

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Proteomics

The Josep Carreras Leukaemia Research (IJC) Institute Proteomics Core is located on the Can Ruti campus, providing an exceptional translational research niche. The IJC Proteomics Core provides state-of-the-art mass spectrometry-based proteomics services to characterize and quantify proteomes, proteins, and their post-translational modifications. We offer proteomics services to Institute scientists and to external public and private organizations, delivered by a highly committed team.

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Bioinformatics

The IJC Bioinformatics Unit offers both the IJC and external researchers high-quality computational analysis services that cover all aspects of the project related to clinical and biological data. This includes experimental design and data analysis for next-generation microarray experiments and sequencing, statistical consulting, data integration, interpretation, and reporting, as well as software development and scientific database management. Our team consists of qualified professionals with extensive experience in bioinformatics and research and experienced developers. The unit has access to high-performance computing resources and works closely with the Genomics and Single Cell units.

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Genomics

The IJC Genomics Unit aims to provide scientific services to the IJC community as well as external researchers. Various technologies have been implemented in the Unit to evaluate the relevant genomic and epigenomic characteristics in order to unravel the basic molecular mechanisms of the disease and contribute to the discovery of therapeutic targets and biomarkers. The Genomics Unit is equipped with state-of-the-art technology to offer solutions in both epigenomic and translational and genomic studies in many types of samples (primary cells, cell lines, frozen and paraffin-embedded tissues, etc.). We have extensive experience in DNA-based genome-wide methylation analysis, and we also perform pyrosequencing for DNA analysis. We use next-generation sequencing (NGS) technology to investigate subsets of genes or specific regions of the genome with the Illumina MiSeqDx system.

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Molecular cytogenetics

The Cytogenetics Unit of the Josep Carreras Leukemia Research Institute is headed by Dr. Francesc Solé. The Cytogenetics Unit includes the Cytogenetics Laboratory of the Catalan Institute of Oncology (ICO).

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Single Cell

The single cell unit is equipped with state-of-the-art instruments for isolating a cell and preparing libraries. We are a scientific and technological support unit for high-level research projects in the field of Single Cell Genomics and will assist researchers from experimental design to data analysis. OUR MISSION The mission of the Single Cell Unit is to facilitate academic research by offering services based on cutting-edge unicellular technologies and space genomics. Unicellular genomics represents a powerful tool for the analysis of complex tissues and has significantly advanced our knowledge in basic and clinical sciences. The Single Cell Unit will support the scientific community using the most advanced technology for unicellular analysis.

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PAM – Affimetrix Microarray Unit

The Microarray Unit (MU) is a service focused on DNA and RNA microarray solutions towards personalized medicine