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Common Services (ACTC+Molecular Biology)

The objective of the Common Services Unit is to provide optimal spaces and equipments to support IDIBELL staff research. The unit also offers specific working laboratories as Biosafety Level 2 rooms, to work with specific biological agents, and a Radioactivity Installation, in order to guarantee a safe working environment.

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Biobank IDIBELL

The HUB-ICO-IDIBELL Biobank is a public, non-profit establishment that was created with the aim of managing and regulating the different collections of biological samples collected at the Bellvitge University Hospital (HUB), in the Duran i Reynals Hospital (ICO) and other associated centers, in accordance with current regulations (Law 14/2007, of 3 July on Biomedical Research and RD 1716/2011, of 18 November). The HUB-ICO-IDIBELL Biobank has been authorized by the General Directorate of Health Planning and Research of the Department of Health of the Generalitat de Catalunya and is registered in the National Register of Biobanks of the Carlos III Health Institute in accordance with RD 1716/2011, which establishes the basic requirements for authorization and operation of biobanks for biomedical research purposes and the treatment of biological samples of human origin. The Biobank is part of the National Network of Biobanks.

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Bioinformatics platform

The IDIBELL Bioinformatics Unit (IBU) started the activity in 2018. Its mission is to provide all researchers at the Bellvitge Campus scientific consulting, methodological support and technological resources on bioinformatics to enhance both the number and the quality of research projects where omics data are involved. We also offer standard services to external community. Our staff has over 15 years’ experience in experimental design, omics and integrative data analyses, databases and ontologies management, pipelines and tools development, as well as a long experience in teaching formal education and training activities in the fields of omics data and bioinformatics.

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Animal facility

IDIBELL Animal facility provides support to researchers who need to use laboratory animals (mice, hamsters and Zebrafish) in their research lines. The Animal facility occupies about 800 m2 and is divided into two units: one to house mice and hamsters, located on the third floor and one to house zebrafish, located on the ground floor.

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Molecular interaction platform

The Molecular Interactions Platform provides scientific-technological support to the scientific community in the field of molecular interactions and biomarker discovery using several approaches. First, Surface Plasmon Resonance (SPR) allows real-time monitoring of any type of molecular interactions (protein-protein, protein-drugs, protein-vesicles, protein-RNA, …) and performs high-precision measurements of affinity and kinetic constants, binding specificity, isotyping and screening of potential medications/drugs. Next, Luminex technology allows the detection of up to fifty different biomarkers at once in biological samples and fluids using the technology of magnetic beads. In addition, metabolism and bioenergetics, driving cellular functions such as cell signalling, proliferation, or cell fate, can be measured with the Seahorse in real-time in living cells. Mitochondrial respiration, glycolysis, ATP rate oxidation and fatty acid oxidation can be measured with high precision. Recently we have acquired a high resolution spatial transcriptomics and proteomics platform,CosMx (Nanostring). CosMx SMI enables rapid quantification and visualization of up to 6,000 RNA and 64 validated protein analytes at single cell resolution in biopsies and tissues samples.Our mission is to provide an integrated support, from experimental design, optimization of assay conditions, experiment execution to data analysis and reporting. Our state-of-the art technology together with the large experience and know-how in biomedical research and protein science are at the service of both internal and external researchers.

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Flow cytometry platform

Our Flow Cytometry facility provides users with the state-of-the-art equipment for flow Cytometry analysis and high-speed cell sorting. Unit personnel support users for experimental design, data analysis and acquisition. Following manufacturer instructions, a proper maintenance and standard quality control procedures are routinely applied to ensure best quality results.

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Electron microscopy platform

The Bioimaging Platform makes advanced optical and electron microscopy equipment and techniques available to IDIBELL researchers for the performance of the maximum number of experiments requested by the various research groups. It provides technical assistance from the design stage of experiments to the analysis of the results obtained.

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Optical microscopy platform

The Bioimaging Platform makes advanced optical and electron microscopy equipment and techniques available to IDIBELL researchers for the performance of the maximum number of experiments requested by the various research groups. It provides technical assistance from the design stage of experiments to the analysis of the results obtained.

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Histology platform

The Histology Platform provides our users with the appropriate infrastructures to carry out the most common histological techniques, such as inclusions, microtomies, colorimetric stains and immunodetections (direct or indirect), as well as to develop other newer or more complex techniques. In addition, it offers the processing of varied samples: cells and colonies grown in monolayer and three-dimensional structures such as embryonic bodies and organoids, obtained in vitro and thin sections of tissues / organs on slides (paraffin sections or cryosections, 3-10 µm) and thick tissue sections to be processed on floating or in toto (30-300µm). The platform allows service requests to be made with technical support, in self-service or in a combined mode, and supports both campus and external users. In addition, it also participates in training tasks, with trainees both from CFGS and university level, and with courses, seminars and workshops.